Take Part in a Parkinson's Study
Be part of clinical research studies evaluating an oral investigational drug to see if it may help improve PD symptoms that impact your movement and daily activities.

Help us complete the breakthrough for Cerevel's most advanced therapeutic candidate, Tavapadon, for the treatment of both early- and late-stage Parkinson’s disease.
Let's Come Together for PD Research
SC3 Research Group, Inc.
About the TemPo Studies
The TemPo Studies are evaluating the efficacy and safety of the investigational drug in two different groups of patients:
People with early stage PD
(diagnosis within the past 3 years) who are not currently taking levodopa or dopamine agonists to manage symptoms
People who are currently taking levodopa to manage PD symptoms
About the Study Drug
Tavapadon is an investigational drug being evaluated for treatment of PD.
Help us complete the breakthrough for the most advanced therapeutic candidate, Tavapadon, for the treatment of both early- and late-stage Parkinson’s disease. Tavapadon was rationally designed as an orally-bioavailable, once-daily partial agonist that selectively targets dopamine D1/D5 receptor subtypes with the goal of balancing meaningful motor activity with a favorable tolerability profile. A chronic neurodegenerative disorder, Parkinson’s primarily results in progressive and debilitating motor symptoms, including decreased bodily movement, slowness of movement, rigidity, tremor and postural instability, all of which result from the death of dopamine-producing neurons in the brain.
Each of the TemPo Studies will compare the investigational drug to placebo. A placebo is an inactive material, such as a sugar pill, that looks like the investigational drug, but does not contain any active drug. Placebos play an important role in clinical research studies, as they help researchers determine if an investigational drug works better or is safer than taking nothing.
Participants in the TemPo Studies will be randomly assigned (like flipping a coin) to receive the investigational drug or placebo. Your chances of receiving the investigational drug or placebo will depend on which of the two TemPo Studies you are participating in. Neither you nor the study doctor will know if you are receiving the investigational drug; however, the study doctor can find out this information if he or she feels it is necessary for your health.
Study Participation Overview
Study participation will take approximately 35 weeks
Screening Period
Up to 31 days
The study doctor and study staff will review your medical history and conduct a number of tests and assessments to determine if you are fully eligible to participate. This visit will last approximately four hours.
Study Treatment Period
27 weeks
You will begin taking your assigned study drug (investigational drug or placebo) as directed by the study doctor. You will be asked to attend ten study visits where you will take part in study-related tests and assessments to monitor your health and the effects (if any) of your assigned study drug. These visits are expected to last approximately one to two hours.
Safety Follow-up Period
Up to 30 days after your final study visit
A member of the study team will contact you by phone for a final check-in.
Eligible study participants will receive the following at no cost:
If you decide to join the TemPo study, your health and safety will carefully be monitored by specialists, and your participation will help doctors evaluate the study drugs to measure it's effectivity.
Study-related consultation and care
Study visits, tests, assessments, and procedures
Study drugs (investigational drug or placebo)
Am I eligible?
You may be eligible to participate in the TemPo Studies if you meet the following eligibility criteria:

Have been diagnosed with PD
less that three years ago
40 to 80 years of age
To participate in the TemPo Studies, you must meet the age requirements.
Have never received deepbrain stimulation treatment
SEE IF YOU ARE ELIGIBLE
To see if you may be eligible to participate in the TemPo Studies, please complete our brief online questionnaire. You must be of legal age to complete this questionnaire.
All health-related information you provide will remain completely confidential and will only be used to determine if you may be eligible to participate.
About SC3 Research Group, Inc.

At SC3 Research, our goal is to advance the discovery of treatments for neurodegenerative disorders. Our website provides you the latest information on actively recruiting clinical research trials at our Pasadena and Reseda clinics.
PRIMARY OBJECTIVE

With clinic locations in Pasadena, Reseda, and Beverly Grove, SC3 Research has a team of dedicated and experienced investigators, raters, clinical research coordinators, and support staff to ensure the safety of study participants and the integrity of study data.
OUR EXPERTISE